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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD10
All Species:
7.58
Human Site:
S389
Identified Species:
12.82
UniProt:
Q14728
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14728
NP_001111.3
455
48339
S389
S
V
V
A
G
Y
G
S
P
G
Q
K
G
T
V
Chimpanzee
Pan troglodytes
XP_517077
405
43118
K340
G
G
E
V
A
A
V
K
R
A
L
L
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001115142
512
54726
G389
S
V
V
A
G
Y
E
G
S
K
A
L
R
D
S
Dog
Lupus familis
XP_545913
642
66749
L576
L
L
V
P
A
F
L
L
I
G
W
G
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2V8
456
49351
S390
T
M
V
S
S
Y
G
S
P
G
Q
K
G
T
I
Rat
Rattus norvegicus
B2RYH9
507
54917
L435
F
I
P
G
P
P
F
L
F
G
A
C
I
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506540
334
35116
Y269
L
S
A
V
V
S
G
Y
G
S
A
G
Q
K
G
Chicken
Gallus gallus
XP_420825
461
49829
A382
L
L
L
Y
S
F
A
A
A
I
V
I
P
C
L
Frog
Xenopus laevis
NP_001088384
454
49524
A377
L
L
L
Y
S
F
A
A
A
I
V
V
P
C
L
Zebra Danio
Brachydanio rerio
NP_001017667
450
48935
S380
A
I
V
V
P
C
L
S
T
Q
V
S
G
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524429
477
51883
T411
A
F
A
V
T
C
L
T
T
L
V
S
K
Y
G
Honey Bee
Apis mellifera
XP_625086
440
48862
T374
M
V
V
T
C
M
M
T
L
V
T
H
I
G
P
Nematode Worm
Caenorhab. elegans
NP_510814
445
49487
P380
S
L
V
H
V
I
Y
P
Q
S
E
K
G
V
L
Sea Urchin
Strong. purpuratus
XP_001181814
396
43728
Q331
H
H
W
F
H
N
R
Q
A
M
I
G
L
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
77.5
55.6
N.A.
80
21.1
N.A.
42.8
64.2
63.2
58.2
N.A.
40
41
38.6
39.3
Protein Similarity:
100
87.9
80.4
58.7
N.A.
85.5
34.5
N.A.
54.2
76.7
77.1
72.9
N.A.
59.7
61.5
60.8
55.1
P-Site Identity:
100
6.6
40
20
N.A.
66.6
6.6
N.A.
6.6
0
0
20
N.A.
0
13.3
26.6
0
P-Site Similarity:
100
6.6
40
40
N.A.
93.3
20
N.A.
6.6
33.3
33.3
33.3
N.A.
13.3
20
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
15
15
8
15
15
22
8
22
0
0
8
0
% A
% Cys:
0
0
0
0
8
15
0
0
0
0
0
8
0
15
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
8
0
8
0
22
8
0
8
0
0
0
0
0
8
% F
% Gly:
8
8
0
8
15
0
22
8
8
29
0
22
29
8
22
% G
% His:
8
8
0
8
8
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
15
0
0
0
8
0
0
8
15
8
8
15
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
8
0
22
8
8
0
% K
% Leu:
29
29
15
0
0
0
22
15
8
8
8
15
22
8
36
% L
% Met:
8
8
0
0
0
8
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
15
8
0
8
15
0
0
0
15
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
8
8
15
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% R
% Ser:
22
8
0
8
22
8
0
22
8
15
0
15
0
0
8
% S
% Thr:
8
0
0
8
8
0
0
15
15
0
8
0
0
22
0
% T
% Val:
0
22
50
29
15
0
8
0
0
8
29
8
0
15
15
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
15
0
22
8
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _